Mechanism
How Photocil Works
For Psoriasis
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For Vitiligo
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A safe & effective topical cream for psoriasis & vitiligo — harnessing the sun’s therapeutic UV right from your own home.
A topical cream that provides clinically-proven relief to psoriasis and vitiligo symptoms — no lamp, no clinic.
Photocil can be used as a standalone treatment (monotherapy) or in combination with existing medications for psoriasis, vitiligo, or atopic dermatitis. Because it works as a purely mechanical sunscreen-like barrier on the skin surface — allowing only therapeutic NB-UVB wavelengths through — it does not interact with, or enter, the body. It does not affect systemic drugs or biologics. In fact, it may enhance their effectiveness by delivering targeted adjuvant phototherapy simultaneously.
Phototherapy has long been an established standard-of-care treatment for psoriasis and vitiligo. Prior to Photocil, it was only available through a UV photo lamp — most commonly administered at a medical clinic.
Photocil cream acts as a precision filter, blocking non-therapeutic solar radiation while selectively allowing the therapeutic NB-UVB wavelengths through to your skin. This gives you the benefits of traditional phototherapy, powered by natural sunlight.
Photocil is steroid free, requires no oral medication and no injections. In clinical trials, patients experienced no side effects.*
*Not available in the U.S. as OTC.
The Dead Sea (400m below sea level) is famous for healing skin conditions because the extra atmosphere filters out harmful low-UVB wavelengths, leaving only therapeutic 311–313nm NB-UVB. Photocil replicates this effect anywhere on earth — two photostable UV-absorbing molecules (α-Glucosyl Hesperidin & DHHB) form a band-pass filter on the skin surface, blocking erythema-causing wavelengths while selectively transmitting therapeutic NB-UVB.
ⓘ US FDA NDC: 54841-001-03 (Applied Biology Inc.). Registered as cosmetic in India (Photofirst™, CDSCO) and LATAM markets. Source: Expert Opinion on Pharmacotherapy, 2014.
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“I live in a small town — there’s no phototherapy clinic nearby, and I simply couldn’t travel to the city three times a week. A dermatologist recommended Photocil and it changed everything. Within 12 weeks I cleared my vitiligo completely at home, in natural sunlight — no steroids, no injections, no clinic visits. Just the cream and the sun.”— Vitiligo Patient, Maharashtra, India
Real patient before & after results from published clinical trials.
Treatment Time: 12 Weeks
Treatment Time: 9 Weeks
Treatment Time: 12 Weeks
Treatment Time: 11 Weeks
Treatment Time: 12 Weeks
Multicenter India Study
“Photocil is a safe & viable treatment for psoriasis & vitiligo patients. Photocil provides an effective alternative to the photo booth.”— Prof. Torello Lotti, MD (Chairman of Dermatology, University of Rome, Italy) —
Photocil is supported by peer-reviewed published research across vitiligo, psoriasis and atopic dermatitis.
Treatment with Photocil is easy. Just follow this simple guide.
Check for sunny conditions and plan for shortest session time (close to noon).
Apply Photocil liberally to affected areas of skin.
Cover non-affected skin with clothing, hat, and SPF 30+ sunscreen.
Proceed outside.
Visit photocil.com/sun or use the Photocil mobile app to begin your session.
Expose skin to direct daylight while the Session System tracks time.
Photocil Session System notifies you when to end your session.
Return inside. That’s it — treatment complete.
Published in Ray-N-Ovation — real-world outcomes from Indian dermatologists using Photofirst™ in clinical practice.
14-year-old boy with vitiligo patches on the anterior abdominal wall. Repigmentation observed at Day 30 following 20-min sunlight sessions (winter) with Photofirst™.
57-year-old male with hypopigmented patches on scalp. Previous treatments included Trioxalen and Tacrolimus. Significant scalp repigmentation after 3 months on Photofirst™ 3×/week.
6-year-old girl with discolored patches on upper eyelid for 3 months. Maternal family history of vitiligo. Used with topical Tacrolimus. Complete repigmentation at 8 weeks.
Peer-reviewed manuscripts, case studies, and the Photofirst™ product monograph — all available to download.
Comprehensive prescribing information, clinical data, pharmacology, dosing protocols, safety profile, and regulatory status for Photofirst™ (Photocil®) — intended for healthcare professionals.
Reach out to San Pellegrino Cosmetics Pvt. Ltd. — India Licensee & Distributor of Photocil®
India Licensee & Distributor for Photocil® (Photofirst™) · Gurugram, Haryana, India